Organic fucoidan is a highly researched and documented marine algal polysaccharide that originates on the cell walls of sea-based plants. It exhibits many immune system supporting characteristics and has been mentioned or involved in over 600 studies found in the National Library of Medicine. These studies suggest that organic fucoidan may help the body in a number of ways including:

  • Promoting natural defenses that protect cells in the body
  • Supporting processes that promote cellular health by protecting the body from potential threats
  • Supporting detoxification and circulatory systems
  • Promoting biological processes that maintains healthy liver function
  • Supports healthy liver function
  • Stabilizes blood sugar levels already in the healthy range

Organic fucoidan also has a large amount of antioxidant components as well as essential amino acids, proteins, minerals and dietary fiber; all of which promote optimal immune system health. Furthermore, it demonstrates its immune system supporting capabilities in a number of ways, such as through its ability to promote ideal interferon gamma levels. These cytokine proteins are produced by white blood cells and they further activate the immune system.

In addition, new studies suggest that organic fucoidan promotes biological processes that support cellular health by helping combat harmful toxins and substances that could cause cell death. It also promotes metabolism, healthy levels of cholesterol already in the healthy range, and helps the body when new cells need to be formed, which is essential for a healthy immune system. Furthermore, its high antioxidant content is quite useful for helping the body fight free radicals. Overall, organic fucoidan supports numerous processes in the body that are essential for optimal health.

Studies on Fucoidan:

  1. Janet Helen Fitton. Therapies from Fucoidan; Multifunctional Marine Polymers. Mar Drugs. 2011; 9(10): 1731–1760. PMCID: PMC3210604 Published online 2011 Sep 30. doi: 10.3390/md9101731
  2. Irhimeh MR, Fitton JH, Lowenthal RM. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul Fibrinolysis. 2009 Oct;20(7):607-10. doi: 10.1097/MBC.0b013e32833135fe.
  3. Giraux JL, Matou S, Bros A, Tapon-Bretaudière J, Letourneur D, Fischer AM. Modulation of human endothelial cell proliferation and migration by fucoidan and heparin. Eur J Cell Biol. 1998 Dec;77(4):352-9.
  4. Moon HJ, Lee SR, Shim SN, Jeong SH, Stonik VA, Rasskazov VA, Zvyagintseva T, Lee YH. Fucoidan inhibits UVB-induced MMP-1 expression in human skin fibroblasts. Biol Pharm Bull. 2008 Feb;31(2):284-9.
  5. J. Helen Fitton, Giorgio Dell’Acqua, Vicki-Anne Gardiner, Samuel S. Karpiniec, Damien N. Stringer and Emma Davis. Topical Benefits of Two Fucoidan-Rich Extracts from Marine Macroalgae. Cosmetics 2015, 2(2), 66-81.
  6. Karim Sennia, Farida Guenichea, Alexandrine Foucault-Bertauda, Sylvie Igondjo-Tchena, Florence Fiorettia, Sylvia Colliec-Jouault, Patrick Duran, Jean Guezenne, Gaston Godeau, Didier Letourneur. Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of connective tissue proteolysis. Archives of Biochemistry and Biophysics; Volume 445, Issue 1, 1 January 2006, Pages 56–64.

Other Research:

  1. Cofrades S, López-López I, Bravo L, Ruiz-Capillas C, Bastida S, Larrea MT, Jiménez-Colmenero F. Nutritional and antioxidant properties of different brown and red Spanish edible seaweeds. Food Sci Technol Int. 2010 Oct;16(5):361-70. doi: 10.1177/1082013210367049. Epub 2010 Sep 10.
  2. Han J, Kang S, Choue R, Kim H, Leem K, Chung S, Kim C, Chung J. Free radical scavenging effect of Diospyros kaki, Laminaria japonica and Undaria pinnatifida. Fitoterapia. 2002 Dec;73(7-8):710-2.
  3. Mak W, Hamid N, Liu T, Lu J, White WL. Fucoidan from New Zealand Undaria pinnatifida: monthly variations and determination of antioxidant activities. Carbohydr Polym. 2013 Jun 5;95(1):606-14. doi: 10.1016/j.carbpol.2013.02.047. Epub 2013 Mar 15.
  4. Fung A, Hamid N, Lu J. Fucoxanthin content and antioxidant properties of Undaria pinnatifida. Food Chem. 2013 Jan 15;136(2):1055-62. doi: 10.1016/j.foodchem.2012.09.024. Epub 2012 Sep 17.
  5. Moreira AS, González-Torres L, Olivero-David R, Bastida S, Benedi J, Sánchez-Muniz FJ. Wakame and Nori in restructured meats included in cholesterol-enriched diets affect the antioxidant enzyme gene expressions and activities in Wistar rats. Plant Foods Hum Nutr. 2010 Sep;65(3):290-8. doi: 10.1007/s11130-010-0179-z.
  6. Hu T, Liu D, Chen Y, Wu J, Wang S. Antioxidant activity of sulfated polysaccharide fractions extracted from Undaria pinnitafida in vitro. Int J Biol Macromol. 2010 Mar 1;46(2):193-8. doi: 10.1016/j.ijbiomac.2009.12.004. Epub 2009 Dec 16.
  7. Rafiquzzaman SM, Kim EY, Kim YR, Nam TJ, Kong IS. Antioxidant activity of glycoprotein purified from Undaria pinnatifida measured by an in vitro digestion model. Int J Biol Macromol. 2013 Nov;62:265-72. doi: 10.1016/j.ijbiomac.2013.09.009. Epub 2013 Sep 20.
  8. Hyun YJ, Piao MJ, Ko MH, Lee NH, Kang HK, Yoo ES, Koh YS, Hyun JW. Photoprotective effect of Undaria crenata against ultraviolet B-induced damage to keratinocytes. J Biosci Bioeng. 2013 Aug;116(2):256-64. doi: 10.1016/j.jbiosc.2013.02.003. Epub 2013 Mar 6.
  9. Liu CL, Lim YP, Hu ML. Fucoxanthin enhances cisplatin-induced cytotoxicity via NFκB-mediated pathway and downregulates DNA repair gene expression in human hepatoma HepG2 cells. Mar Drugs. 2013 Jan 8;11(1):50-66. doi: 10.3390/md11010050.
  10. Okai Y, Higashi-Okai K, Nakamura S. Identification of heterogenous antimutagenic activities in the extract of edible brown seaweeds, Laminaria japonica (Makonbu) and Undaria pinnatifida (Wakame) by the umu gene expression system in Salmonella typhimurium (TA1535/pSK1002). Mutat Res. 1993 Oct;303(2):63-70.
  11. Fujiyuki T, Hamamoto H, Ishii K, Urai M, Kataoka K, Takeda T, Shibata S, Sekimizu K. Evaluation of innate immune stimulating activity of polysaccharides using a silkworm (Bombyx mori) muscle contraction assay. Drug Discov Ther. 2012 Apr;6(2):88-93.
  12. Maruyama H, Tamauchi H, Hashimoto M, Nakano T. Suppression of Th2 immune responses by mekabu fucoidan from Undaria pinnatifida sporophylls. Int Arch Allergy Immunol. 2005 Aug;137(4):289-94. Epub 2005 Jun 17.
  13. Song YS, Li H, Balcos MC, Yun HY, Baek KJ, Kwon NS, Choi HR, Park KC, Kim DS. Fucoidan promotes the reconstruction of skin equivalents. Korean J Physiol Pharmacol. 2014 Aug;18(4):327-31. doi: 10.4196/kjpp.2014.18.4.327. Epub 2014 Aug 13.
  14. Moon HJ, Lee SH, Ku MJ, Yu BC, Jeon MJ, Jeong SH, Stonik VA, Zvyagintseva TN, Ermakova SP, Lee YH. Fucoidan inhibits UVB-induced MMP-1 promoter expression and down regulation of type I procollagen synthesis in human skin fibroblasts. Eur J Dermatol. 2009 Mar-Apr;19(2):129-34. doi: 10.1684/ejd.2008.0611. Epub 2009 Jan 7.
  15. Moon HJ, Lee SR, Shim SN, Jeong SH, Stonik VA, Rasskazov VA, Zvyagintseva T, Lee YH. Fucoidan inhibits UVB-induced MMP-1 expression in human skin fibroblasts. Biol Pharm Bull. 2008 Feb;31(2):284-9.
  16. D’Orazio N, Gemello E, Gammone MA, de Girolamo M, Ficoneri C, Riccioni G. Fucoxantin: a treasure from the sea. Mar Drugs. 2012 Mar;10(3):604-16. doi: 10.3390/md10030604. Epub 2012 Mar 7.

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