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    Black Pepper Fruit Extract (BioPerine®)

    BioPerine® is a standardized black pepper fruit extract that can dramatically augment the bioavailability of vitamins and nutrients by increasing the body’s ability to absorb these supplements.

    According to the BioPerine® manufacturer, “The subtle, yet potent properties of BioPerine® have been measured in several clinical studies with healthy volunteers in the U.S. These studies measured the absorption of three distinct categories of products. The categories evaluated with and without BioPerine® were fat-soluble (beta-carotene), water-soluble (vitamin B6) and a mineral (selenium, in the form of selenomethionine). Gastrointestinal absorption of all the studied nutrients, as measured by amounts present in the blood, increased dramatically when administered with BioPerine® as compared to the control group receiving the nutrient alone.”

    Black Pepper Fruit:

    • Exhibits strong antioxidant activity
    • Decreases inflammation
    • Acts as an antioxidant
    • Displays anti-cancer benefits
    • Reduces tumors
    • Promotes a healthy immune system
    • Prevents carcinogenesis
    • Reduces oxidative stress to the cells

    Additional Research

    • “Both water extract (WEBP) and ethanol extract (EEBP) of black pepper exhibited strong total antioxidant activity.”[101]
    • “Overall, these results suggest that black pepper and its constituents like hot pepper, exhibit anti-inflammatory, antioxidant and anticancer activities.”[102]
    • “Our findings strongly suggest that black pepper and cardamom exert immunomodulatory roles and antitumor activities, and hence they manifest themselves as natural agents that can promote the maintenance of a healthy immune system. We anticipate that black pepper and cardamom constituents can be used as potential therapeutic tools to regulate inflammatory responses and prevent/attenuate carcinogenesis.”[79]
    • “The data indicate that supplementation with black pepper or the active principle of black pepper, piperine, can reduce high-fat diet induced oxidative stress to the cells.”[27]


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    These statements have not been evaluated by the FDA. These products are not intended to prevent,
    treat, cure, or diagnose any disease. Information on this site is for educational
    purposes only. It is not medical advice. Consult a physician if you
    seek medical advice or have a medical problem.